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Persistent URL http://purl.org/net/epubs/work/49470
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Record Id 49470
Title CHAINSAW: a program for mutating pdb files used as templates in molecular replacement
Abstract Abstract CHAINSAW is a model editing program for use in Molecular Replacement. Given a sequence alignment between template and target, it modifies the template structure on a residue by residue basis by pruning non-conserved residues while leaving conserved residues unchanged. Three degrees of pruning are possible. An internal alignment algorithm is used to cope with any residues which may be missing from the X-ray structure. CHAINSAW has been successfully used as a tool to assist in solving a number of protein structures.
Organisation CSE , CCP4 , STFC
Keywords molecular replacement , protein structure , model editing , Biology
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Language English (EN)
Type Details URI(s) Local file(s) Year
Journal Article J Appl Crystallogr 41, no. 3 (2008): 641-643. doi:10.1107/S0021889808006985 2008
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