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Full Record Details
Persistent URL
http://purl.org/net/epubs/work/49545
Record Status
Checked
Record Id
49545
Title
Putting pressure on elusive polymorphs and solvates
Contributors
IDH Oswald
,
I Chataigner
,
S Elphick
,
FPA Fabbiani
,
AR Lennie (STFC)
,
J Maddaluno
,
WG Marshall (STFC)
,
TJ Prior
,
CR Pulham
,
RI Smith (STFC)
Abstract
The reproducible crystallisation of elusive polymorphs and solvates of molecular compounds at high pressure has been demonstrated through studies on maleic acid, malonamide, and paracetamol. These high-pressure methods can be scaled-up to produce bulk quantities of metastable forms that can be recovered to ambient pressure for subsequent seeding experiments. This has been demonstrated for paracetamol form II and paracetamol monohydrate. The studies also show that the particular solid form can be tuned by both pressure and concentration.
Organisation
ISIS
,
ISIS-POLARIS
,
STFC
Keywords
Physics
,
Materials
,
Chemistry
Funding Information
Related Research Object(s):
Licence Information:
Language
English (EN)
Type
Details
URI(s)
Local file(s)
Year
Journal Article
CrystEngComm
11, no. 2 (2009): 359-366.
doi:10.1039/b814471k
2009
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