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Persistent URL http://purl.org/net/epubs/work/55864
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Record Id 55864
Title xtalPiMS: a PiMS-based web application for the management and monitoring of crystallization trials
Abstract Abstract A major advance in protein structure determination has been the advent of nanolitre-scale crystallization and (in a high-throughput environment) the development of robotic systems for storing and imaging crystallization trials. Most of these trials are carried out in 96-well (or higher density) plates and managing them is a significant information management challenge. We describe xtalPiMS, a web-based application for the management and monitoring of crystallization trials. xtalPiMS has a user-interface layer based on the user interface standards of the Protein Information Management System (PiMS) and a database layer which links the crystallization trial images to the meta-data associated with a particular crystallization trial. The user interface has been optimized for the efficient monitoring of high-throughput environments, but it could also be adapted for use without robotic imagers. The database can either be an instance of a PiMS database or (as is the case at the Division of Structural Biology in Oxford) a legacy database for which a suitable mapping layer has been developed.
Organisation CSE , STFC
Keywords Biology , LIMS , crystallogenesis , protein , crystallography , ISIS 1987
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Language English (EN)
Type Details URI(s) Local file(s) Year
Journal Article Journal of Structural Biology 175 (2011) 230¿235. 10.1016/j.jsb.2011.05.008 xtalPims.pdf 2011