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Persistent URL http://purl.org/net/epubs/work/41415
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Record Id 41415
Title MrBUMP: An automated pipeline for molecular replacement
Abstract A novel automation pipeline for macromolecular structure solution by Molecular Replacement is described. There is a special emphasis on the discovery and preparation of a large number of search models, all of which can be passed to the core Molecular Replacement programs. For routine Molecular Replacement problems, the pipeline automates what a crystallographer might do, and its value is simply one of convenience. For more difficult cases, the pipeline aims to discover the particular template structure and model edits required to produce a viable search model, and may succeed in finding an efficacious combination that would be missed otherwise. We give an overview of MrBUMP, and highlight some recent additions to its functionality.
Organisation CCLRC , CSE , CCP4
Keywords Biology , protein crystallography , molecular replacement
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Language English (EN)
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Journal Article Acta Crystallogr D 64 (2007): 119-124. doi:10.1107/S0907444907037195 2007