The open archive for STFC research publications

Full Record Details

Persistent URL http://purl.org/net/epubs/work/41453
Record Status Checked
Record Id 41453
Title Activation and protonation of dinitrogen at the FeMo cofactor of nitrogenase
Abstract The protonation of N2 bound to the active center of nitrogenase has been investigated using state-of-the-art density-functional theory calculations. Dinitrogen in the bridging mode is activated by forming two bonds to Fe sites, which results in a reduction of the energy for the first hydrogen transfer by 123 kJ/mol. The axial binding mode with open sulfur bridge is less reactive by 30 kJ/mol and the energetic ordering of the axial and bridged binding modes is reversed in favor of the bridging dinitrogen during the first protonation. Protonation of the central ligand is thermodynamically favorable but kinetically hindered. If the central ligand is protonated, the proton is transferred to dinitrogen following the second protonation. Protonation of dinitrogen at the Mo site does not lead to low-energy intermediates.
Organisation CCLRC
Keywords Physics , Chemistry , Biology
Funding Information
Related Research Object(s):
Language English (EN)
Type Details URI(s) Local file(s) Year
Journal Article J Phys Chem 123 (2005): 074306. doi:10.1063/1.2008227 2005
Showing record 1 of 1