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Persistent URL http://purl.org/net/epubs/work/65212
Record Status Checked
Record Id 65212
Title Lyophilised protein dynamics: more than just methyls?
Contributors
Abstract The movement of molecules on the fast pico- (ps) to nano- (ns) second time scale in proteins affects the slower, larger lengthscale dynamics involved in protein folding and biological function. As a result, detailed understanding of structure-dynamics-function relationships requires the use of theoretical models that incorporate the full dynamic complexity of a bio-material. To advance such models we have used neutrons to probe protein dynamics on the ps-ns timescale in a series of proteins: apoferritin (Apo), insulin (Ins), superoxide dismutase (SOD) and green fluorescent protein (GfP). Our results hint at a protein structure dependent dynamic landscape.
Organisation ISIS , ISIS-ILL , STFC
Keywords biophysics , Physics , quasi-elastic neutron scattering , Biology
Funding Information
Related Research Object(s):
Language English (EN)
Type Details URI(s) Local file(s) Year
Journal Article ILL Annual Report 2012 (2012): 42-43. http://www.ill.eu…ontents.htm?rub=3_44 2012
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